Heatmap from Scientific Research

26 TCGA HNSC patients with 3 types integrated at 35 sites. Inner gray ring: each arc indicates a patient. Middle ring: individual HPV integration sites, with color representing HPV type. Outer ring: heatmap of expression of genes within 500 kbp of each integration site in the patient with HPV integration (peripheral) and 4 randomly selected patients without HPV integration around that gene (central). Values show Z -score of TPM values of each gene among the 5 samples. Red marks outside the heatmap: genes with outlier expression in the patient with HPV integration. Gene symbols: genes with outlier expression. Color of the gene symbols indicate their CERES score. Red symbols indicate genes with negative CERES scores, essential to tumor viability. Black symbols indicate genes not assessed by Project Achilles.

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