Heatmap from Scientific Research

ATAC-seq peaks in a 1-Mbp window centered on SiHa’s integration site. Each column shows a 200-bp genomic window overlapping a peak. We generated all 200-bp genomic windows with a stride of 50 bp which overlapped a peak in any of the 5 cell lines. (Top) : ATAC-seq FPM and CTCF ChIP-seq log2 fold enrichment over control for each cell line divided by the cell line’s corresponding maximum value in chromosome 13. (Middle) : Difference in the epigenome of SiHa and the most extreme value in the other 4 cell lines when SiHa had the most extreme value among the cell lines. When SiHa did not have the most extreme value, we used white. (Bottom) : Physical location of peaks. Black lines map every 100 kbp to the corresponding peak. Red dashed line: HPV integration site.

DOI