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The simulated tree and CNPs (red: duplication, blue: deletion, brown: normal), where coloured tips represent patient samples taken at different time points (T_0) , (T_1 = T_0 + n_1 * dt) , and (T_2 = T_1 + n_2 * dt) , with dt , (n_1) , and (n_2) being integers and (1<= n_1, n_2 <= 6 (the number of samples))
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