Heatmap from Scientific Research

Two examples (chr3:188,727,296-189,775,872) and (chr3:185,057,280-186,105,856) of cell-type specific predictions in H1-hESC and GM12878. Two regions are selected from the overlapped region of Akita held-out test set and Epiphany’s test chromosomes. Columns from left to right: contact map in H1ESc, same region in GM12878, and the absolute difference between the two cell types (H1-GM12878). Rows from top to bottom: Ground truth matrices with Akita normalization, Akita prediction, ground truth with HiC-DC+ observed-over-expected count ratio, Epiphany prediction of observed-over-expected count ratio. Akita predictions were obtained from the multi-task output, and Epiphany predictions were generated with model trained on GM12878.

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