Workflow from Scientific Research

Comparison of sequence conservation and gene organisation between the ancient and modern reference (NC_047913.1) genomes of Mushuvirus mushu . Black lines indicate alignments with small gaps. The height of the middle plot depends on the identity between genomes. The lowest similarities (grey colour) were concentrated in a 600-nucleotide variability region of the Hoc-like gene affected by the diversity-generating retroelement (DGR) mechanism. Two major structural differences in the ancient and modern genomes constituted an additional codon stop in a gene of unknown function (genome position: 9518) and 17 nucleotide insertion/deletions, which changed the open reading frame in the tail length tape measure protein.

DOI