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Sensitivity analysis of the causal effect of childhood body mass index (BMI) on adult neuroticism score in the ALSPAC cohort. Estimates are from the primary (IVW) analysis and sensitivity analyses (MR-Egger, weighted median, and mode-based estimator). The x-axis represents the causal effect (beta) of childhood BMI on adult neuroticism. The y-axis represents the standard error of the causal effect estimate. Each point represents the estimate and standard error from a different MR method. IVW=inverse variance weighted; MR=Mendelian randomization; ALSPAC=Avon Longitudinal Study of Parents and Children.

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