Protein Structure from Scientific Research

Analysis of polyclonal immune responses against the HIV trimer 2 weeks after vaccination with BG505 SOSIP. Composite figures from NS EMPEM analysis of polyclonal responses when the HIV trimer was incubated with 1, 0.25 mg, or 0.075 mg polyclonal sera immediately or for 24 h. Composite figures are shown for samples that were complexed with (+CL) or without (-CL) a photo-cross-linker. A color-coding scheme for antibodies targeting different epitope clusters is shown in the left panel. The HIV trimer is represented in gray.

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