Forest Plot from Scientific Research

Forest plots per study and test and overall prediction of diagnostic yield. Squares represent predicted diagnostic yields and whiskers represent 95% CrI. The size of the square is proportional to the number of participants with MAD-positive tuberculosis in each study, and studies are sorted by size. The vertical dashed lines indicate the overall predicted mean by the random effects model and the diamond represents the 95% CrI around that prediction. The PT/MAD represents the number of participants with a positive test from the first sample collected in the initial 2 days after enrolment divided by the number of positive participants as defined by the harmonised MAD based on microbiologically confirmed tuberculosis. 95% CrI=95% credible interval. AlereLAM=Alere Determine TB LAM Ag assay. MAD=meta-analysis denominator. PT=positive tests. Xpert=Xpert MTB/RIF or Xpert Ultra assay. *Data are from the Kraaifontein Tuberculosis substudy. tData are from the Antiretroviral Therapy Tuberculosis substudy.

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