Scatter Plot from Scientific Research

Variant immunostaining intensities in the presence of VX-445 are plotted against the corresponding intensities in the presence of vehicle. The relative positions of variants with deficient (red), intermediate (gray), and robust (blue) PME are shown for reference. Thermodynamic projections for the minimum (red dashes) and maximum shifts (blue dashes) in variant intensities are shown based on the projected surface immunostaining intensity of fully folded CFTR (ffold= 1, black dashes). Measurements represent the average of three biological replicates and error bars reflect the standard deviation.

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