Line Plot from Scientific Research

Mean ERK activity after activation of opto-RTK in WM858 (left) and WM983B (right) cells. Cells were treated with Vem (1 μM)/Cobi (100 nM) together with DMSO, SOSi (RMC-0331, 1 μM; BI-3406, 1 μM), SHP2i (RMC-4550, 1 μM), or ERKi (SCH772984, 1 μM) 24 h before time-lapse imaging. Data represent mean ± 95% CI (n > 150 cells for each condition).

DOI