Illustration from Scientific Research

Wild-type sequence of the 125 bp mrc1a enhancer is shown, annotated with colors highlighting the Ets, Sox, and NHR binding motifs. Schematic depicts enhancer-reporter constructs in which each class of motif or control regions was targeted by mutation. Red X’s denote the location of targeted sites. mp-GFP, mouseBeta-globin minimal promoter fused to GFP.

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