Protein Structure from Scientific Research

Top views of the superposition of the X-ray structure of Fy-4 (yellow) and Fy-4 bound in the FERRY complex (red). Inset shows a close-up of the binding cleft for the vertical helix of Fy-2 (blue), formed by the two Fy-4 protomers. Upon Fy-2 binding, a loop region of Fy-4 moves sideways to accommodate the vertical helix of Fy-2.

DOI