Scatter Plot from Scientific Research

Scatter plot quantitation of hypomethylation signal by nanopore sequencing, comparing leukocyte-depleted blood samples from patients with either metastatic (F) or localized prostate cancer before surgical resection or radiation therapy (G) versus blood samples from healthy age-matched male donors (HDs). Error bar denotes mean with SEM. p value assessed by two-tailed Student’s t test. Dotted lines indicate the thresholds of hypomethylation signal that encompass all healthy donors tested, with the fraction of cancer patients with hypomethylation signal above those thresholds considered positive.

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