Heatmap from Scientific Research

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Heatmap (upper; hypomethylation shaded yellow) and matched quantitative scatter plots (lower) of single-cell DNA methylation levels within all 1,496 prostate cancer PMDs, showing progression from normal prostate to localized prostate cancer (GS6 and GS8) and metastatic CTCs. TheCD1A-IFI16locus (dashed vertical red line) shows early and profound demethylation, starting at GS6, with its rank number across all PMDs at each tumor stage shown in parentheses (red).

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