Scatter Plot from Scientific Research

Ranking of methylation level at 40 core PMDs (red dots) among all 1,496 total PMDs as a function of timeline from normal prostate to localized (GS6 and GS8) and metastatic cancers (CTCs), showing the early demethylation of core PMDs. Within normal prostate, all 40 core PMDs have methylation level >75%, and 31 are hypomethylated as early as GS6.

DOI