Chemical Structure from Scientific Research

The interactions between the peptide ligands and NK3R are shown as spheres and dotted lines (red to NK3R's N-terminus, purple to NK3R's ECL2, and brown to NK3R's ECL3). The specific interactions between the N-termini of the ligands and the ECLs of NK3R contribute to the more potent activation by NKB and senktide than by SP.

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