OR (for logistic regressions) and beta values (for linear regressions) associated with variant presence from multivariable regression analyses of autism diagnosis, SCQ t-score, IQ score bin, autism factors and developmental milestones, stratified by gene type and autism OR of genes carrying the variants (Methods). Regressions performed on individuals from the SSC and SPARK samples. To correct for the biased sex ratio among individuals with autism, with approximately one female to four males, sex was added as a covariate. Error bars correspond to 95% CI. P values associated with each beta value were corrected for multiple testing using the false discovery rate (FDR) method (full circles correspond to corrected P < 0.05). The number of individuals with available data is shown for each regression. For age at developmental milestones, age is given in months and higher values indicate higher age.
