Line Plot from Scientific Research

d–f, When the pre-planned MMRM parallel group analysis (first dosing period only, placebo n = 14, AEF0117 n = 6 per dose) was performed to eliminate the sequence effect, a significant decrease was observed for all the outcomes (Treatment x Time, P = 0.0381 (d), P = 0.0032 (e), P = 0.0126 (f); Treatment x Dose x Time, P = 0.0368 (e)).

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