Line Plot from Scientific Research

In monkeys (left panel, n = 4), AEF0117 dose-dependently decreased the number of THC infusions (4 g kg -1 per infusion). * P < 0.001, # P = 0.002 compared to vehicle (three sessions average), Tukey test. In monkeys (right panel, n = 4), after extinction of THC-reinforced responding, AEF0117 decreased reinstatement of drug seeking induced by a non-contingent THC injection (40 g kg -1 , i.v.). $ P = 0.0346, $$ P = 0.0015 compared to non-contingent saline; ## P = 0.0023, P = 0.0018 in AEF0117 5 g kg -1 and 15 g kg -1 , respectively, ### P = 0.0002 compared to THC + vehicle (AEF0117 0 g kg -1 ), Dunnett test, within-subjects design.

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