Cox models assessing the doseresponse per 280 g per week higher usual alcohol intake within current drinkers, were stratified by age at risk and study area and were adjusted for education and smoking. Each solid square represents HR with the area inversely proportional to the variance of the log HR. The horizontal lines indicate 95% CIs. Diseases considered to be alcohol-related by the WHO are indicated with 'W' under the 'WHO' column. The individual diseases listed included all that showed FDR-adjusted significant associations with alcohol (FDR-adjusted P < 0.05, indicated with 'Y' under the 'FDR sig.' column) and WHO alcohol-related diseases that showed nominally significant associations with alcohol (P < 0.05). All P values are two-sided. Included less-common ICD-10 codes within the corresponding ICD-10 chapter that were not individually investigated in the present study. 'Less-common psychiatric and behavioral conditions' consisted of ICD-10 codes F00-F99, excluding F32, F33 and F99. 'Less-common circulatory diseases' consisted of ICD-10 codes I00-I99, excluding I10, I11, I20, I21, I24, I25, I27, I42, I46, I48-I51, I60-I67, I69, I70, I80 and I83. 'Less-common injury, poisoning and other external causes' consisted of ICD-10 codes S00-T98, excluding S06, S09, S22, S32, S42, S52, S62, S72, S82, S92 and T14.
