Bubble Plot from Scientific Research

Circles represent separate studies, with the size of the circle proportional to the number of events (KFRT, GFR < 15 ml min -1 per 1.73 m 2 or doubling of serum creatinine). The colors of circles indicate intervention types. The black line is the line of regression through the studies. Blue lines are the 95% pointwise Bayesian prediction bands computed from the model. Red triangles indicate studies where the estimated treatment effects are beyond the margins. Albiminura Targ, albuminuria-targeted protocol; CE, clinical endpoint; CI, confidence interval; Endothelin rec. A, endothelin receptor antagonist; Immunosuppress, immunosuppression; Mineralcort rec., mineralocorticoid receptor antagonist; Nurse cood., nurse-coordinated care; PI, prediction interval.

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