Temporal expression of mouse chromatin regulator genes homologous to the human genes that are perturbed in hPSC-derived neurons ( d ) across multiple neuron subtypes in the mouse neocortex. UP, upper layer; DL, lower layer; CPN, callosal projection neurons; SCPN, subcerebral projection neurons; NP, near projecting; CThPN, cortico-thalamic projection neurons. **** P < 0.0001, *** P < 0.001, ** P < 0.01, * P < 0.05. NS, not significant. n and P values in d and e are reported in Supplementary Tables 2 and 3 . Two-tailed one sample t -test ( d ); Welch’s one-way ANOVA with Games–Howell’s multiple comparisons test ( e ).
