Logistic regression (inverse-variance-weighted; IVW) association results for multiple epidemiologic risk factor exposures with the TAAD outcome in two-sample MR analyses. The lifetime smoking TAAD OR reflects a per-genetic increase in smoking ~20 cigarettes a day for 15 years and stopping 17 years ago. The OR for height reflects a 1-s.d. genetic increase in standing height (~7.6 cm). The SBP, DBP, MAP and PP ORs correspond to the change in TAAD risk per 10-mmHg increase in the blood pressure trait. The lipid ORs reflect the change in TAAD risk per s.d. genetic increase in lipid fraction. Two-sided P values are displayed, and we set a two-sided P < 0.0055 (0.05 / 9 traits) for statistical significance. Error bars represent 95% CIs of the displayed ORs.
