Clustered from Scientific Research

Genes associated with biological rhythms process were differentially regulated in CADM1 -mutant cells. RNA-seq of mutant CADM1 -transduced cells reveals the most upregulated process associated with the 425 differentially expressed genes was biological rhythms. Clock genes associated with E-box factors and RORE target genes are highlighted by brackets. Graph shows the fold change of mRNA expression relative to UT cells for genes associated with this process in WT and mutant CADM1 (453-amino acid isoforms).

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