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IgAN risk alleles (green), prioritized positional candidate genes (gray), related genes in PPI (for example, ligands/receptors) or same pathway (yellow), targeting drugs approved or currently in clinical trials including agonists and antagonists (blue) and diseases targeted by these drugs (orange). High-priority targets defined in Fig. 5 are indicated by an asterisk. GWAS loci with candidate causal genes not targeted by existing drugs are not depicted.

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