Forest Plot from Scientific Research

Excluding HLA region. The traits are organized by immune-mediated (blue), infectious (green) and cardiometabolic (orange) categories and sorted based on the genetic correlation coefficient (r g ). The data are presented as r g point estimates (center) with bars corresponding to 95% CIs. PSC, primary sclerosing cholangitis; MN, membranous nephropathy; SLE, systemic lupus erythematosus; IBD, inflammatory bowel disease; MS, multiple sclerosis; UC, ulcerative colitis; T1D, type 1 diabetes; AS, ankylosing spondylitis; RA, rheumatoid arthritis; Chol, total serum cholesterol levels; TG, total serum triglycerides levels; LDL, low-density lipoprotein levels; BUN, blood urea nitrogen; eGFR Cr, estimated glomerular filtration rate using serum creatinine levels; T2D, type 2 diabetes; BMI, body mass index; eGFR cystatin, estimated glomerular filtration rate using serum cystatin levels; HTN, essential hypertension; FEV1/FVC, forced expiration volume at 1 s over forced vital capacity; CAD, coronary artery disease. The asterisk indicates nominal two-sided P < 0.05 for a test of genetic correlation without multiple testing correction. Supplementary Table 13 provides references to all GWAS used in this analysis along with the statistics for each correlation test.

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