Whisker movement assessment. Both left and right whiskers scored 3 for all WT ( n = 5 male (M), 4 female (F), Gata2 KO/flox ;Phox2b-Cre + ( n = 2 M, 3 F), Gata3 tlz/flox ;Phoxb2-Cre + ( n = 2 M, 4 F) and cRE2 Fam5 snv/snv ( n = 2 M, 4 F) mice). Both left and right whiskers scored 0 for all cRE1 dup/+ mice ( n = 8 M, 10 F). Of the cRE1 dup/+ ; Gata3 tlz/flox ;Phox2b-Cre + rescue mice ( n = 1 M, 6 F), 2 had full (3) and 1 had no (0) whisker movement bilaterally, whereas the remaining 4 had intermediate movement (0 < x < 3). Pairwise, two-sided Bonferroni’s corrected Wilcoxon’s test ( P values as shown). The filled circle shows mean and the error bar the s.e.m. Schemas in j were created with BioRender.com .
