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Strategy for identifying genomic regions forming many contacts specific to either GAM or Hi-C. We counted how often a genomic region was an anchor point in the set of GAM-specific contacts, Hi-C-specific contacts or strong-and-common contacts. The 10% of genomic windows with the highest absolute difference between the number of GAM-specific and Hi-C-specific contacts were classified as Hi-C-preferred regions or GAM-preferred regions, respectively. Similarly, the top 10% of strong-and-common contacts were used to define common regions that participate to a similar extent in strong contacts seen in both methods.
#Heatmap#Bar Plot#Genomic regions#GAM#Hi-C#Contacts#Anchor point#Genomic windows#Hi-C-preferred regions#GAM-preferred regions#Common regions
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