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Total bile acids of serum and portal serum ( n =5 mice per group); one-way ANOVA with Bonferroni’s multiple comparison test (serum total BAs: WT vs Mdr2 -/-, 95% CI -238,281 to -83,938, P < 0.0001; Mdr2 -/- vs Mdr2 -/- +DSS, 95% CI 31,605–185,948, P = 0.0044; portal serum total BAs: WT vs Mdr2 -/-, 95% CI -537,812 to -240,590, P < 0.0001; Mdr2 -/- vs Mdr2 -/- +DSS, 95% CI 200,324–497,546, P < 0.0001).
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