Open-loop passivity for fish treated with ketamine, with or without α1 adrenergic blocker prazosin (100 μM). All error bars denote SEM.*p< 0.05,**p< 0.01,n.s. p> 0.4. ΔF (Zscored) for each fish was calculated as the difference between mean total fluorescence before treatment subtracted to total fluorescence at a specific time point, divided by the standard deviation of total fluorescence before treatment, for hindbrain mask (D). Two-way ANOVA with Sidak’s multiple comparison test.n= 7 (control-prazosin and ketamine-prazosin), 9 (ketamine-vehicle), 11 (control-vehicle).p= Interaction (0.0140), 0.0057 (ket-prazosin vs. ket-vehicle), 0.9947 (control-vehicle. vs. control-prazosin).
