Heatmap of differential gene expression (≥ twofoldchange, p ≤ 0.05, q ≤ 0.05) of between HERVE 6q15 +/+ and HERVE 6q15 / A498 cells ( left ). Columns represent independent replicates. Gene ontology (GO) functional annotation of the differentially expressed genes ( right ) ( p values calculated with g:Profiler using hypergeometric distribution tests and adjusted for multiple hypothesis testing using the g:SCS (set counts and sizes) algorithm, integral to the g:Profiler server [ 33 ].
