The effect of SA8 (100 nM, except for K V 10.1 and Na V 1.7 which were tested at 1 M) on the peak currents was reported as the RCF. Bars represent the mean of 3–6 independent measurements; error bars indicate the SEM. Data are shown for the following channels: Hk V 1.1 ( n = 4), hK V 1.2 ( n = 4), hK V 1.3 ( n = 3), hK V 10.1 ( n = 4), hK V 11.1 ( n = 5), mK Ca 1.1 ( n = 4), hKCa3.1 ( n = 6), hTRPA1 ( n = 5), hTRPV1 ( n = 5), and hNa V 1.7 ( n = 5) (for details of the expression systems, solutions, and voltage protocols, see Materials and Methods, and for raw current traces see Additional File 13 : Figure S9). SA8 did not inhibit any of the investigated channels at the applied concentrations. Supporting data values are available in Additional File 3 : File S1
