Heatmap from Scientific Research

Matrix of empirically derived (1000 replicates) p values for distribution of effect size differences between pathway-partitioned (Mendelian) instruments and tissue-partitioned (coloc) instruments in 1-sample and 2-sample MR setting (univariable and multivariable) using body mass index (BMI) and blood pressuresystolic (SBP) and diastolic (DBP) as exposures and cardiometabolic traits as outcomes (AF, CHD, MI, HF, stroke, T2D, LDVEDV, LVEF, LVESV, SV). p values < 0.05 are highlighted in dark red

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