(Upper left heatmap): Correlation cluster heat map of differential metabolites and microbial groups, the abscissa is microbial groups, the ordinate is differential metabolites, * P < 0.05, ** P < 0.01, red means negative correlation, and blue means positive correlation. The deeper the color is, the stronger the correlation is. (Lower left heatmap): Heatmap of relative abundance of microbial groups at the phylum level. Rows represent samples, row names represent group names, and columns represent microbial groups. From purple to blue, relative abundance changes from low to high. (Upper right heatmap): Heatmap of the abundance of differential metabolites. Rows represent differential metabolites, columns represent samples, and column names represent group names. From green to red, relative abundance changes from low to high.