Microscopy from Scientific Research

Illustration of experimental design. Sonic hedgehog PDOX medulloblastoma (Med-1712FH) mouse models were generated by seeding tumour cells in mouse cerebellum. Mice received a 7-day course of Palbociclib and compared to untreated control tumours. H&E-stained images display regions of human tumour and mouse brain in Palbociclib-treated mice (demarcated Palbociclib A and Palbociclib B) and controls (demarcated Control C and Control D). Contrast-enhanced MRI shows the tumour location in PDOX mouse brain (outlined in red). Palbociclib-treated and control sections are indicated with stars and squares, respectively.

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