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Lollipop plot of the splice-altering variants identified by Introme in the ZERO childhood cancer cohort [ 28 ] for genes RB1, made using ProteinPaint [ 29 ]. Each circle represents the location of at least one genetic variant identified as reportable and splice-altering in the ZERO cohort (red: somatic variant, blue: germline variant). Shaded areas on the transcript represent protein domains.
#Illustration#Lollipop Plot#Splice Altering Variants#Introme#ZERO Childhood Cancer Cohort#RB1#ProteinPaint#Genetic Variant#Somatic Variant#Germline Variant#Protein Domains
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