Line Plot from Scientific Research

The performance of each tool is shown using precision recall curves (PRCs) of functionally validated splice-altering and non-splice-altering variants, grouped by the class of the variant. PRCs compare the precision (proportion of calls that are relevant) and recall (proportion of total relevant variants that are called) across different score thresholds, with better performing tools appearing near the top right. Variants that impacted the polypyrimidine tract or branchpoint were classified as impacting the acceptor splice site (3'SS). 5'SS: donor splice site; ESE/ESS: exonic Splicing Enhancer/Silencer.

DOI