Heatmap of CGIs differentially methylated between Holstein Friesian and Nelore and/or between taurine (Holstein Friesian and N'Dama) and Nelore. CGIs were restricted to those within 2000 bp of a TSS and where the mean expression of the nearest gene was >10 TPM across all samples. The RNA-seq log2FC is the log2 fold change between the mean Holstein Friesian RNA-seq signal and the mean Nelore RNA-seq signal, where positive log2FC (red points) indicate higher expression in the Holstein Friesian cattle and negative log2FC (blue points) indicate higher expression in the Nelore cattle. Bcell = B cell, CD4 = CD4 T cell, CD8 = CD8 T cell, gdT = ?δ T cell, NK = NK cell, mono = monocyte and gran = granulocyte