2-d histogram showing CMImpute (top row) and species baseline (bottom row) probe-wise correlation as a function of mean inter-tissue probe variance when considering the subset of highest-coverage probes. Each row contains four heatmaps corresponding to variance quartiles. Within each variance quartile, the heatmap shows the number of probes with a certain probe variance ( x -axis) and certain probe-wise correlation ( y -axis) split into 50 bins along each axis. Each quartile is labeled with its own color bar. Color bar scales for each quartile are consistent across methods. Remaining baselines can be found in Additional file 2: Fig. S11. Corresponding plot when considering all probes can be found in Additional file 2: Fig. S12a.
