Persistent (24 h post-washout) effects of (left) phencyclidine-site NMDA receptor antagonists and (right) 5-HT2A receptor agonists. All error bars denote SEM.n.s. p> 0.05,*p< 0.05,**p< 0.01,***p< 0.005,****p< 0.001. Statistics for (L) and (M) one-way ANOVA with Tukey’s multiple comparison test (vs. control). (L, left),n= 17 (control), 10 (ketamine), 8 (MK-801),p= 0.0086 (ketamine), and 0.0115 (MK8-801). (L, right) 16 (control), 8 (DOI), 7 (TCB-2),p= <0.0001 (DOI), and 0.0008 (TCB-2). (M, left)n= 8 (control), 8 (ketamine), 8 (MK-801),p= 0.0103 (ketamine), <0.0001 (MK-801). (M, right)n= 16 (control), 8 (DOI), 8 (TCB-2),p= 0.8096 (DOI), and 0.8295 (TCB-2).