Bar Plot from Scientific Research

Mature miR-199a-5p (K) and miR-335-3p (L) expression in endothelial cells overexpressing the wild type, edited or the backbone (controlOE; pcDNA3.1(+)) pri-mir-199a-1 or pri-mir-335 constructs depicted in (H, n = 5). Data are presented as mean SEM for n biological independent replicates. Experimental groups were compared using a two-tailed Mann-WhitneyUtest or one-way ANOVA followed by Holm-Sidak’s multiple comparison test for pairwise comparisons (B). (A–G)*p < 0.05; versus scrambled or IgG IP.#p < 0.05; versus siADAR2. (H–L)*p < 0.05 versus controlOEor wild-type pri-mir-199a1/pri-mir-335 as determined by pairwise t test (I and J) or Bonferroni’s multiple comparison test (K and L).#p < 0.05 versus wild-type pri-mir-199a1/pri-mir-335 as calculated by Bonferroni’s multiple comparison test. See alsoFigures S7ES7H.

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