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Open access visualization of Workflow, Illustration, S-EABR Construct, SARS-CoV-2 S Protein, Furin Cleavage Site
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Sequence information for S-EABR construct. Top: the SARS-CoV-2 S protein (including a furin cleavage site, 2P stabilizing substitutions, the D614G substitution, and CT, a cytoplasmic tail deletion) is fused to an EPM sequence, a (Gly)3Ser (GS) spacer, and an EABR sequence. EPM, endocytosis prevention motif; GS, (Gly)3Ser linker; EABR, ESCRT- and ALIX-binding region. Bottom: EPM and EABR sequence information.

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