Bar Plot from Scientific Research

Schematic of the experiment and qRT-PCR ofIl24andVegfamRNA in YFP(Hif1WT) or YFP+(Hif1exon2) FACS-purified EpdSCs from homeostatic skin and from day-1 wounds ofKrt14CreER; Hif1fl/fl; RosaYFP+/flmice treated with topical 4OH-Tam (n = 5 mice). White dotted lines: epidermal-dermal border; wound site, red dotted line; epidermal migration direction, red arrow. DAPI, nuclei; scale bars except for the boxed regions: 100 μm. Data in (B) and (D) are presented as mean ± SEM. Experiments were performed ≥ 3×. Statistical significance was determined using two-tailed unpaired Student’s t tests;****p < 0.0001;*p < 0.05. See alsoFigures S6.

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