Protein Structure from Scientific Research

For the H3447R CTR-RELN variant the model was determined by a homology-based model of WT CTR-RELN that was calculated by Swiss-Model. Position 3,447 orients in the same direction as most other arginines (magenta). Arginines in positions 3,446, 3,453 and 3,457 (cyan) may also interact with heparin as part of the heparin-binding motif but are oriented differently from most basic amino acids.

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