Heatmap from Scientific Research

Anatomical details of Tau burden in the temporal cortex. Flat map representations of the right hemisphere temporal lobe cortex for regions of interest (ROIs) (top left, ERC), with Tau PET (FTP) overlay for four cases. The asymptomatic PSEN1 -E280A carrier was 38 years old; the PSEN1 -E280A carrier with typical MCI was 44 years old. The male carrier of RELN-COLBOS was notable for having relatively lower Tau burden in the medial temporal regions (ERC and PPC), compared to typical PSEN1 -E280A mutation carriers.

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