Scatter plot of for ARG-derived independent variants associated with aspartate aminotransferase in the GOT1 gene (estimated within 337,464 samples) against for their WES partners (estimated within 138,039 samples). We color points based on whether the WES partner is likely causal in WES-50K-imp (imputation from WES-50K into ~459,000 samples 43 ), not likely causal but marginally significant in WES-50K-imp or not marginally significant in WES-50K-imp ('ARG only'). We also plot the for the additional likely causal variants in WES-50K-imp against the in WES-138K. Bars represent fractions in c and means in d . Error bars represent 1.96 s.e.m. in b and f and represent bootstrap 95% CIs in c and d . Additional results are shown in Extended Data Fig. 9 . HDL, high-density lipoprotein; LDL, low-density lipoprotein.
