Forest Plot from Scientific Research

Forest plots representing Mendelian randomization associations between cardiovascular risk factors and CAD (n cases = 181,522; n controls = 984,168). Association estimates (β; center of the error bars) obtained from Mendelian randomization analyses using the IVW method are represented on the x axis. The range of each bar represents the 95% CI. Unadjusted P values from the associations obtained by two-sided Wald test are indicated. n = 340,159 (SBP), 340,162 (DBP), 359,983 (BMI), 315,133 (HDL), 343,621 (LDL), 343,992 (triglycerides (TG)), 164,638 cases and 195,068 controls (smoking (SMK)) and 74,124 cases and 824,006 controls (type 2 diabetes (T2D)). The asterisks indicate significance after Bonferroni correction for testing nine traits (P < 5.6 × 10 −3 ) (Supplementary Table 13).

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