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Recurrence analysis in TR14 (n = 25) cells displayed as the fraction of cells containing a detected circular DNA from each circular DNA type. ecDNA was defined as circular DNAs overlapping with copy number-amplified regions identified in bulk sequencing (green) and mtDNA or chrM (red). 'Others' are defined as all other small circular DNAs (blue). Data are presented as the mean s.e.m.
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