Illustration from Scientific Research

Schematic drawings of zebrafish embryo phenotypes. -BMP loss of function causes reduced and often curled tails, +RA gain-of-function embryos lack head structures and have shortened tails, -Wnt leads to enlarged heads and shortened tails, -FGF causes loss of mesoderm and tail tissue, -Nodal embryos lack mesoderm and have cyclopia, -Shh embryos frequently have mispatterned somites and cyclopia, and -PCP leads to a shortened and widened body axis, manifested, for example, by shorter somites.

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