PSNR and NRMSE comparisons across techniques. All comparisons with XTC, PSNR: Slice 2p ( P = 2.0 x 10 -34 ), NLM ( P = 2.1 x 10 -7 ), Deconvolution (Deconv.) ( P = 1.4 x 10 -13 ), BM3D ( P = 10 -22 ) and N2V ( P = 5.7 x 10 -9 ); NRMSE: Slice 2p ( P = 2.0 x 10 -50 ), NLM ( P = 10 -6 ), Deconv. ( P = 3.9 x 10 -14 ), BM3D ( P = 2.8 x 10 -28 ) and N2V ( P = 2.6 x 10 -8 ); n = 80 images per condition, one-way analysis of variance with Bonferroni correction for multiple comparisons. * * * P < 0.001. Box-plot elements are defined as follows: center line (median); box limits (upper and lower quartiles); whiskers (1.5x interquartile range); points represent individual cropped images (points outside of whiskers are outliers). Sample outputs shown in Extended Data Fig. 6 .
